Welcome to Neuroscience Center Zurich

Prof. Dr. Klaas Enno Stephan



Translational Neuromodeling Unit (TNU)
Institute for Biomedical Engineering
University of Zurich & ETH Zurich

Wilfriedstrasse 6
CH-8032 Zurich

Tel. +41 44 634 9125

Main Goals, Keywords

Translational neuromodeling: Developing computational models of brain (dys)function as tools for clinical applications (diagnostics and treatment prediction).

Group Members

1 professor,1 senior physician, 7 postdoctoral fellows, 5 PhD students, 1 technician, 2 administrators.

Previous and Current Research

Our goal is to establish mathematical models that infer subject-specific mechanisms of brain disease from non-invasive measures of behaviour and neuronal activity.

These models aim to quantify both physiological and computational principles that underlie (mal)adaptive cognition, such as aberrant learning and decision-making, in individual subjects.

The long-term goal is to use these models for a mechanistic re-definition of psychiatric and neurological diseases, leading to pathophysiologically interpretable diagnostic classifications and individual treatment predictions.


Techniques and Equipment

Techniques: statistical parametric mapping (SPM) computational modelling, dynamic causal modeling, fMRI, EEG, MEG.

Equipment: 3T & 7T fMRI scanners, 2x 128 channel EEG systems, behavioural lab, neurophysiological lab (TMS/tDCS), pharmacological lab, high-performance computer cluster, research clinic for patient studies.

Selected Lectures, Seminars or Colloquia

Selected Publications


René and Susanne Braginsky Foundation, European Union FP-7, NCCR "Neural Repair and Plasticity", Clinical Research Priority Programs “Multiple Sclerosis” and “Molecular Imaging".



Wichtiger Hinweis:
Diese Website wird in älteren Versionen von Netscape ohne graphische Elemente dargestellt. Die Funktionalität der Website ist aber trotzdem gewährleistet. Wenn Sie diese Website regelmässig benutzen, empfehlen wir Ihnen, auf Ihrem Computer einen aktuellen Browser zu installieren. Weitere Informationen finden Sie auf
folgender Seite.

Important Note:
The content in this site is accessible to any browser or Internet device, however, some graphics will display correctly only in the newer versions of Netscape. To get the most out of our site we suggest you upgrade to a newer browser.
More information

© 2015 ETH Zurich | Imprint | Disclaimer | 21 October 2013