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Prof. Dr. Dr.med. Klaas Enno Stephan

 

klaas_stephan_web

Translational Neuromodeling Unit (TNU)
Institute for Biomedical Engineering
University of Zurich & ETH Zurich

Wilfriedstrasse 6
CH-8032 Zurich

Tel. +41 44 634 9125

stephan@biomed.ee.ethz.ch

Main Goals, Keywords

Translational neuromodeling: Developing computational models of brain (dys)function as tools for clinical applications (diagnostics and treatment prediction).

Group Members

1 professor,1 senior physician, 7 postdoctoral fellows, 5 PhD students, 1 technician, 2 administrators.

Previous and Current Research

Our goal is to establish mathematical models that infer subject-specific mechanisms of brain disease from non-invasive measures of behaviour and neuronal activity.

These models aim to quantify both physiological and computational principles that underlie (mal)adaptive cognition, such as aberrant learning and decision-making, in individual subjects.

The long-term goal is to use these models for a mechanistic re-definition of psychiatric and neurological diseases, leading to pathophysiologically interpretable diagnostic classifications and individual treatment predictions.

stephan

Techniques and Equipment

Techniques: statistical parametric mapping (SPM) computational modelling, dynamic causal modeling, fMRI, EEG, MEG.

Equipment: 3T & 7T fMRI scanners, 2x 128 channel EEG systems, behavioural lab, neurophysiological lab (TMS/tDCS), pharmacological lab, high-performance computer cluster, research clinic for patient studies.

Selected Lectures, Seminars or Colloquia

http://www.neuroscience.ethz.ch/research/computation_modeling/stephan

Selected Publications

Funding

René and Susanne Braginsky Foundation, European Union FP-7, NCCR "Neural Repair and Plasticity", Clinical Research Priority Programs “Multiple Sclerosis” and “Molecular Imaging".

URL

http://www.translationalneuromodeling.org



 

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© 2014 ETH Zurich | Imprint | Disclaimer | 21 October 2013
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